Promethazine HCl and Codeine Phosphate Oral Remedy is indicated with the momentary relief of coughs and higher respiratory signs and symptoms associated with allergy or maybe the common cold in patients 18 yrs of age and more mature.
Codeine has small plasma protein binding with about seven to 25% of codeine certain to plasma proteins. Codeine passes the blood Mind barrier plus the placental barrier. Tiny quantities of codeine and its metabolite, morphine, are transferred to human breast milk.
Promethazine hydrochloride and codeine phosphate should be presented into a Expecting girl provided that Evidently necessary.
If one will not be out there, you may blend drugs with Filth, espresso grounds, or cat litter, then put the mixture in a sealed plastic bag and toss the bag inside the trash.
Tend not to consider promethazine/codeine Until it has been prescribed for you by a healthcare supplier. Get it as prescribed.
Lifestyle-threatening respiratory despair and Demise have occurred in kids who acquired codeine; most situations followed tonsillectomy and/or adenoidectomy, and a lot of of the children had evidence of getting an ultra-speedy metabolizer of codeine as a result of a CYP2D6 polymorphism. (5.3) Promethazine HCl and Codeine Phosphate Oral check here Remedy is contraindicated in kids young than twelve a long time of age and in children young than 18 years of age following tonsillectomy and/or adenoidectomy.
Like other codeine goods, codeine linctus may be behavior-forming and can result in addiction or overdose.
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Neuroleptic malignant syndrome (NMS) which may lead to death. Tell you healthcare service provider without delay When you have any click here of the next symptoms of NMS:
Codeine is among the By natural means transpiring phenanthrene alkaloids of opium derived with the opium poppy; it is assessed pharmacologically to be a narcotic analgesic.
Stimulation can be obvious, especially in young children and geriatric individuals. Convulsions may possibly almost never come about. A paradoxical-sort response is noted in kids acquiring solitary doses of 75 mg to 125 mg orally, characterised by hyperexcitability and nightmares.
Convey to your health practitioner If you're pregnant or Feel click here you could be pregnant. During pregnancy, this item just isn't advised. It might harm an unborn child. Discuss with your medical professional with regards to the challenges and advantages of this medication. See also Warning more info segment.
Withdrawal indications can arise in breastfed infants when maternal administration of an opioid is stopped, or when breastfeeding is stopped.
This drugs may perhaps contain aspartame. In case you have phenylketonuria (PKU) or another issue that requires here you to limit your consumption of aspartame (or phenylalanine), speak to your physician or pharmacist regarding the Harmless use of the drugs.